Prevention & lipidsCross-sectional study
Association of menopausal status and menopausal hormone therapy with cardiovascular risk factors prevalence in a large French urban population
- Cross-sectional analysis of a prospective cohort study
- age-adjusted
Authors' conclusion
Menopausal women exhibited an increase in all modifiable CVRF compared with non-menopausal women. Menopausal hormone therapy use may have a beneficial effect on the prevalence of these risk factors.
Study context
- Population
- Women aged 40–70 without previous CVD, CARVAR 92 cohort, Hauts-de-Seine, France, 2010–20237,395 women analysed
- Participants
- 16,879 participants
- Exposure
- Non-menopausal vs Menopausal vs Menopausal using menopausal hormone therapy (MHT)
- Non-menopausaln = 2,607reference
- Menopausaln = 4,788
- Outcome
- CV risk factor prevalence
Main finding
As reported in the abstract
Menopausal vs Non-menopausalOdds ratio (95% CI)P value
obesity
1.44(1.21–1.70)
P < 0.001waist obesity
1.33(1.17–1.53)
P < 0.001hypertension
1.17(1.01–1.36)
P = 0.049diabetes mellitus
1.84(1.31–2.61)
P < 0.001dyslipidaemia
1.74(1.49–2.03)
P < 0.001Observational data: associations, not effects.
Original publication
Association of menopausal status and menopausal hormone therapy with cardiovascular risk factors prevalence in a large French urban population. Eur J Prev Cardiol. Published 29 July 2025. doi:10.1093/eurjpc/zwaf460
Summarised from the published abstract; every number is checked against it