Prevention & lipidsCohort study
Association of modifiable lifestyle risk factors with high-sensitivity troponin T and I concentrations and clinical outcomes
- Cohort study
- single-centre
Authors' conclusion
Increasing numbers of modLRF are associated with elevated concentrations of hsTnT and I, whilst the predictive capability of troponins varied according to the presence of modLRF.
Study context
- Population
- Patients undergoing coronary angiography with available hsTnT/I concentrations and modifiable lifestyle risk factors (modLRF) information (overweight, physical inactivity, poor Mediterranean diet adherence, current smoking)
- Participants
- 1,716 patients
- Exposure
- Burden of modifiable lifestyle risk factors
- Outcome
- All-cause mortality and MACE; association of modLRF with hsTnT/I
Main finding
As reported in the abstract
hsTnT/I concentrations and outcomes by modLRF burden
Median hsTnT, overall
15.0 ng/L (IQR 8.0, 29.0)
Median hsTnI, overall
7.6 ng/L (IQR 3.3, 18.6)
Observational data: associations, not effects.
Original publication
Association of modifiable lifestyle risk factors with high-sensitivity troponin T and I concentrations and clinical outcomes. Eur J Prev Cardiol. Published 26 November 2024. doi:10.1093/eurjpc/zwae374
Summarised from the published abstract; every number is checked against it