Heart failure & cardiomyopathiesSecondary analysis
Association of pre-admission exercise habit with post-discharge outcomes for older patients with heart failure
- Secondary analysis of the FRAGILE-HF study
- post hoc analysis
Authors' conclusion
Exercise habits before hospitalization were significantly associated with better strength and physical function and lower post-discharge all-cause mortality in older adult patients with heart failure.
Study context
- Population
- Patients aged ≥65 years hospitalized for HF decompensation
- Participants
- 1,262 patients
- Comparison
- Pre-admission exercise habit vs no exercise habit
- Non-exercise habitn = 587reference
- Primary endpoint
- All-cause mortality
- Follow-up
- Post-discharge
Primary result
As reported in the abstract
Exercise habits vs without: significantly lower all-cause mortality (log-rank test)
P = 0.019
Pre-hospital exercise and lower mortality risk: adjusted Cox HR
0.75 (95% CI 0.58-0.98; P = 0.035)
Further findings
Physical function (grip strength, gait speed, SPPB score)
- Consistently better physical function in the exercise habit group
History of HF hospitalizations and other comorbidities
- No significant differences
Original publication
Association of pre-admission exercise habit with post-discharge outcomes for older patients with heart failure. Eur J Prev Cardiol. Published 19 February 2025. doi:10.1093/eurjpc/zwaf069
Summarised from the published abstract; every number is checked against it