Coronary disease & ACSCohort study
Association of Race and Ethnicity With High-Potency P2Y12 Inhibitors Prescription Among Patients With Acute MI Undergoing Percutaneous Coronary Intervention (PCI): An Analysis From the CathPCI Registry
- registry analysis
- consecutive patients
- logistic regression adjusted for social deprivation index and other patient- and procedure-related variables
Authors' conclusion
In a contemporary national registry of hospitalized patients with AMI who underwent PCI, Black and Hispanic patients were less likely to be discharged on a high-potency P2Y12 inhibitor irrespective of socioeconomic status. These findings highlight an opportunity to achieve equity in guideline-directed AMI pharmacotherapies to improve outcomes.
Study context
- Population
- Patients with AMI who underwent PCI in the NCDR Cath PCI registry, April 2018 to June 2023patients hospitalized with AMI and who underwent PCI
- Participants
- 1,662,387 patients
- Exposure
- Racial and ethnic differences in high-potency P2Y12 inhibitor prescription on discharge
- Blackn = 165,579
- Asiann = 58,595
- Whiten = 1,302,576reference
- Hispanicn = 135,637
Main finding
As reported in the abstract
High-potency P2Y12 inhibitor prescription at discharge · discharge
Prescribed a high-potency P2Y12 inhibitor at discharge
876 078 (52.7%)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted odds ratio | |
|---|---|---|
| High-potency P2Y12 inhibitor discharge prescription, by race — Black vs White · less likely | 0.93 (95% CI 0.92–0.94) | |
| High-potency P2Y12 inhibitor discharge prescription, by race — Asian vs White · more likely | 1.08 (CI 1.07–1.10) | |
| High-potency P2Y12 inhibitor discharge prescription, by ethnicity · less likely | 0.95 (95% CI 0.93–0.96) | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Association of Race and Ethnicity With High-Potency P2Y12 Inhibitors Prescription Among Patients With Acute MI Undergoing PCI: An Analysis From the CathPCI Registry. Circ Cardiovasc Interv. Published 2 January 2026. doi:10.1161/circinterventions.125.015600
Summarised from the published abstract; every number is checked against it