Acute cardiac care & resuscitationCohort study
Association of rescue breathing with outcomes in adult suffocation-related cardiac arrest
- retrospective cohort study
- Inverse probability of treatment weighting (IPTW)
- prespecified subgroup analyses
Authors' conclusion
In suffocation-related OHCA, the type of bystander CPR was not associated with improved neurological recovery. These findings suggest that the type of bystander CPR alone may not be the primary determinant of recovery, although the relative contributions of CPR type, airway management, and other prehospital factors remain to be clarified.
Study context
- Population
- Adult patients with witnessed suffocation-related OHCA, All-Japan Utstein Registry (2005–2023), excluding cardiac-origin cases and those treated by EMS personnel
- Participants
- 76,774 patients
- Exposure
- CCV-CPR and No cardiopulmonary resuscitation (CPR) vs CC-CPR
- CC-CPRn = 39,451reference
- CCV-CPRn = 8,182
- No CPRn = 29,141
- Outcome
- Favorable neurological status
- Follow-up
- One month
Main finding
As reported in the abstract
Each group vs CC-CPREstimate (95% CI)
No CPRAfter IPTW adjustment
adjusted OR 1.20(1.04–1.38)
CCV-CPRno significant difference
OR 1.01(0.78–1.32)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | CC-CPR | CCV-CPR | No CPR | OR (95% CI) | |
|---|---|---|---|---|---|
| One-month survival · secondary outcome | 8.3% | 7.2% | 9.5% | 1.20 (1.12–1.28) | |
| 0.512Odds ratio (log scale) |
ROSC · secondary outcome
One-month survival
- No significant difference for CCV-CPR
Return of spontaneous circulation (ROSC)
- No significant differences were observed for ROSC
Subgroup and sensitivity analyses
- Findings were consistent in subgroup and sensitivity analyses using multiple imputation
Original publication
Association of rescue breathing with outcomes in adult suffocation-related cardiac arrest. Resuscitation. Published 26 June 2026. doi:10.1016/j.resuscitation.2026.111189
Summarised from the published abstract; every number is checked against it