Valvular & structural heart diseaseResearch article
Association of right atrioventricular coupling and right atrial stiffness indices with outcomes in secondary tricuspid regurgitation patients
- Not stated
Authors' conclusion
In STR patients, RAVC and RA stiffness indices are associated with the risk of events, with RAVCVOL yielding the strongest association.
Study context
- Population
- Patients with mild-to-severe secondary tricuspid regurgitation (STR)75 ± 13 years, 58% severe
- Participants
- 513 patients
- Comparison
- Association of right atrioventricular coupling (RAVC) indices (RAVCSTE, RAVCVOL) and right atrial (RA) stiffness index with a composite outcome of all-cause mortality or heart failure hospitalization
Main finding
As reported in the abstract
Composite endpoint:
- All-cause mortality
- Heart failure hospitalization
Patients reaching the composite endpoint
195 patients (38%)
Further findings
Cut-off values associated with increased 2-year event rates (spline curve modelling)
- RAVCSTE
- < 0.82
- RAVCVOL
- > 1.23
- RA stiffness index
- > 4.6
Independent association with the outcome (multivariable Cox regression and hierarchical χ2 analyses)
- only RAVCVOL maintained a significant association with the outcome
- P < 0.05
Original publication
Association of right atrioventricular coupling and right atrial stiffness indices with outcomes in secondary tricuspid regurgitation patients. Eur Heart J Cardiovasc Imaging. Published 27 February 2026. doi:10.1093/ehjci/jeag062
Summarised from the published abstract; every number is checked against it