Coronary disease & ACSCohort study

Association of Smoking Cannabis With Cardiovascular Events Among Veterans With Coronary Artery Disease

CirculationPublished

  • Prospective cohort study
  • survey nonresponse and propensity score-based weights

Authors' conclusion

In this cohort of older veterans with coronary artery disease, self-reported cannabis use was not independently associated with increased cardiovascular events over a mean of 3.3 years of follow-up.

Study context

Population
Older veterans (66 to 68 years) with CAD, born 1950 to 1952
Participants
4,285 veterans
Exposure
Smoking cannabis vs not smoking cannabis
  • Smoking cannabisn = 1,015
  • No cannabis smokingn = 3,122reference
Outcome
Composite of:
  • Fatal and nonfatal stroke
  • Fatal and nonfatal acute MI
  • CV death
Follow-up
Mean 3.3 years

Main finding

As reported in the abstract

Adjusted hazard ratio

0.87

95% CI 0.61–1.24

Smoking cannabis vs No cannabis smoking
adjusted HR 0.87 (95% CI 0.61–1.24)
Total events
563

Observational data: associations, not effects.

Further findings

Composite outcome, any form of cannabis use vs nonuse (past 30 days)

Any form of cannabis use not associated with the composite outcome

Original publication

Association of Smoking Cannabis With Cardiovascular Events Among Veterans With Coronary Artery Disease. Circulation. Published 21 July 2025. doi:10.1161/circulationaha.124.073193

Summarised from the published abstract; every number is checked against it