Prevention & lipidsCohort study
Associations between occupational physical activity and left ventricular structure and function over 25 years in CARDIA
- Prospective cohort study
- longitudinal
Authors' conclusion
The paradoxically adverse association of OPA with cardiovascular health was partially supported by null or adverse associations between high OPA and echocardiogram outcomes.
Study context
- Population
- CARDIA participants aged 30.4 ± 3.4 years at baseline (Year 5 exam, 1990–91); 50.0% female, 56.4% White
- Participants
- 1,462 participants
- Exposure
- 25-year occupational physical activity (OPA) trajectories
- No OPAn = 770reference
- Medium OPAn = 410
- High OPAn = 282
- Outcome
- Left ventricular (LV) structure and function by echocardiography (LVMi, LVEDVi, LVESVi, LVEF, LVSVi, EA ratio), adjusted for baseline values, demographic/health characteristics and leisure time physical activity (LTPA)
- Follow-up
- 25 years
Main finding
As reported in the abstract
- LVESVi (higher)
- β 1.84; P < 0.05
- LVEF (lower)
- β −1.94; P < 0.05
- OPA not significantly associated with LVMi, LVEDVi, LVSVi or EA ratio
- P > 0.05
Observational data: associations, not effects.
Original publication
Associations between occupational physical activity and left ventricular structure and function over 25 years in CARDIA. Eur J Prev Cardiol. Published 9 November 2023. doi:10.1093/eurjpc/zwad349
Summarised from the published abstract; every number is checked against it