Cardio-oncology & otherCross-sectional study

Associations Between Social Determinants of Health and Cardiovascular Health of U.S. Adult Cancer Survivors

JACC CardioOncolPublished

  • Cross-sectional study
  • survey-specific multivariable Poisson regression

Authors' conclusion

An unfavorable SDOH profile was independently associated with worse CVH among adult cancer survivors in the United States.

Study context

Population
US adult cancer survivors (excluding nonmelanotic skin cancer only), National Health Interview Survey 2013–2017representing 10,887,989 persons
Participants
8,254 survivors
Exposure
Highest vs lowest social determinants of health (SDOH) quartile
Outcome
Worse CVH (7-item score based on AHA Life's Essential 8)

Main finding

Worse CVH

Relative risk

1.30

95% CI 1.25–1.35

P < 0.001

Highest SDOH quartile vs Lowest SDOH quartile
RR 1.30 (95% CI 1.25–1.35); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

Worse cardiovascular health (CVH) by age, sex and race (subgroup)

Significantly stronger association in younger participants
P for interaction = 0.026
Significantly stronger association in women
P for interaction = 0.001
No significant interaction with race
P for interaction = 0.051

Worse CVH, by SDOH domain

Higher scores in all SDOH domains independently associated with worse CVH
all P < 0.001

Each CVH component

Higher SDOH scores independently associated with each CVH component (highest SDOH quartile)
all P < 0.05

Original publication

Associations Between Social Determinants of Health and Cardiovascular Health of U.S. Adult Cancer Survivors. JACC CardioOncol. Published 24 October 2023. doi:10.1016/j.jaccao.2023.07.010

Summarised from the published abstract; every number is checked against it