Arrhythmias & electrophysiologyResearch article
Atrial fibrillation burden: a new outcome predictor and therapeutic target
- Narrative review
Authors' conclusion
In addition to anticoagulation and treatment of cardiovascular conditions, AF burden reduction emerges as a therapeutic goal.
Study context
- Population
- Patients with atrial fibrillation (AF)
- Comparison
- Device-detected AF, low AF burden vs Paroxysmal AF vs Persistent and permanent AF
Main finding
As reported in the abstract
Stroke rate without anticoagulation, by AF type and burden
Device-detected AF, low AF burden
1%/year
Paroxysmal AF
2%/year
Persistent and permanent AF
3%/year
Further findings
AF burden-reducing interventions
- Early rhythm control reduces CV events incl. stroke and HF in recently diagnosed AF with CV conditions
- In HF and AF, early rhythm control and AF ablation reduce mortality and HF events
Original publication
Atrial fibrillation burden: a new outcome predictor and therapeutic target. Eur Heart J. Published 2 July 2024. doi:10.1093/eurheartj/ehae373
Summarised from the published abstract; every number is checked against it