Arrhythmias & electrophysiologyCase-control study
Atrial fibrillation in embolic stroke of undetermined source: role of advanced imaging of left atrial function
- Retrospective case-control study
- single-centre
- risk prediction model
- internal validation by bootstrapping
Authors' conclusion
The novel PADS score can identify the risk of AF on prolonged monitoring with ILR following ESUS and should be considered a dedicated risk stratification tool for decision-making regarding the screening strategy for AF in stroke.
Study context
- Population
- Patients with embolic stroke of undetermined source (ESUS) referred for implantable loop recorder (ILR) implantation, December 2009 to September 2019293 stroke, 30 TIA
- Participants
- 323 patients
- Outcome
- AF detection on ILR monitoring; risk prediction model for AF (PADS score)
- Follow-up
- Mean 710 days
Main finding
As reported in the abstract
PADS score for AF identification
- Atrial fibrillation (AF) of any duration detected
- 47.1%
- Lateral PA (increasing), OR
- 1.011
- Age (increasing), OR
- 1.035
- Diastolic BP (higher), OR
- 1.027
- Left atrial (LA) reservoir strain (abnormal), OR
- 0.973
- Model discrimination, AUC
- 0.72
- Bootstrap internal validation (1000 samples of 150 patients), AUC
- 0.73
Observational data: associations, not effects.
Original publication
Atrial fibrillation in embolic stroke of undetermined source: role of advanced imaging of left atrial function. Eur J Prev Cardiol. Published 11 July 2023. doi:10.1093/eurjpc/zwad228
Summarised from the published abstract; every number is checked against it