Arrhythmias & electrophysiologyCohort study

Atrial fibrillation increases left and right atrial pressures in patients with chronic heart diseases

ESC Heart FailPublished

  • single-center retrospective analysis
  • propensity score matching

Authors' conclusion

In our cohort, AF increased PCWP by 2.6 mmHg and RAP by 1.1 mmHg. Furthermore, a previous history of AF is linked to higher atrial pressures in patients later in SR.

Study context

Population
Patients with chronic heart diseases undergoing right heart catheterization (RHC)two propensity-matched cohorts for pulmonary capillary wedge pressure (PCWP) and right atrial pressure (RAP) analysis · PCWP cohort 496 · RAP cohort 494
Participants
1,452 patients
Exposure
Atrial fibrillation (AF) vs sinus rhythm (SR) group

Main finding

As reported in the abstract

PCWP

P < 0.001

Observational data: associations, not effects.

Further findings

RAP · higher in AF · After matching

P = 0.02

Robustness to unmeasured confounders

PCWP E-value
10.8
RAP E-value
2.78

PCWP and RAP in SR cohort by prior history of AF

Significantly higher PCWP and RAP with prior history of AF compared to no AF history

Original publication

Atrial fibrillation increases left and right atrial pressures in patients with chronic heart diseases. ESC Heart Fail. Published 8 January 2026. doi:10.1093/eschf/xvaf032

Summarised from the published abstract; every number is checked against it