Valvular & structural heart disease
Atrial Functional Tricuspid Regurgitation in Patients Undergoing Transcatheter Aortic Valve Replacement
Authors' conclusion
In TAVR patients, afTR is an independent predictor for TR persistence. Moreover, TR persistence is associated with increased 3-year all-cause mortality.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR) for severe AS (January 2013 to December 2020) with concomitant at least moderate tricuspid regurgitation (TR) at baselineof 3,474 TAVR patients
- Participants
- 363 patients
- Exposure
- Atrial functional tricuspid regurgitation (afTR) vs non-afTR
- afTRn = 178
- non-afTRn = 185reference
- Outcome
- TR development after TAVR
Main finding
TR improvement after TAVR
Adjusted odds ratio
2.80
95% CI 1.66–4.76
P < 0.001
By group
afTRvs non-afTR
adjusted OR 2.80 (95% CI 1.66–4.76); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
Aggravation of TR after TAVR
P = 0.013
All-cause mortality, TR persistence vs TR improvement · 3 years
- Significantly higher with TR persistence than with TR improvement
- P < 0.001
Original publication
Atrial Functional Tricuspid Regurgitation in Patients Undergoing Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. Published 8 January 2024. doi:10.
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