Valvular & structural heart diseaseCohort study
Baseline characteristics and outcomes of rheumatic mitral valve disease: the EURObservational Research Programme Valvular Heart Disease II Survey
- Prospective observational registry study
- international
- multicentre
- longitudinal
- 222 centres
Follow-up at 6 months at the investigating centre or by telephone
Authors' conclusion
Compliance with guideline recommendations for intervention is poor overall in patients with rheumatic valve disease.
Study context
- Population
- Patients with severe rheumatic mitral valve disease or previous rheumatic mitral valve intervention in the ESC valvular heart disease (VHD) II registry
- Participants
- 470 vs 332
- Exposure
- Severe rheumatic mitral valve disease vs Previous rheumatic mitral valve intervention
- Severe rheumatic mitral valve diseasen = 470
- Previous rheumatic mitral valve interventionn = 332
Main finding
As reported in the abstract
Intervention in patients with Class I recommendation; mortality
Intervention undertaken in patients with Class I recommendation
70%
Total in-hospital mortality
1.5%
Total mortality at 6 months
3.5%
Observational data: associations, not effects.
Further findings
Independent predictors of death at 6 months
- Age, chronic pulmonary disease, NYHA class III–IV at presentation, liver dysfunction, previous MI
Original publication
Baseline characteristics and outcomes of rheumatic mitral valve disease: the EURObservational Research Programme Valvular Heart Disease II Survey. Eur Heart J. Published 11 February 2025. doi:10.1093/eurheartj/ehaf050
Summarised from the published abstract; every number is checked against it