Cardio-oncology & otherRandomised controlled trial

Behaviorally Designed Gamification and Physical Activity Among Breast and Prostate Cancer Survivors

JACC CardioOncolPublished

  • Randomised controlled trial
  • remotely delivered
  • 24-week intervention and 12-week postintervention period
  • Enrolled between May 2022 and February 2025
  • Mean age 64 years; 81% women, 64% Black, 35% Hispanic

Authors' conclusion

Gamification increased physical activity compared with attention control in Black and Hispanic cancer survivors

Study context

Population
Black and Hispanic breast and prostate cancer survivors after cardiotoxic cancer therapy with ≥1 CV risk factor
Participants
74 vs 76
Comparison
Behaviorally designed gamification vs attention control
  • Gamificationn = 74
  • Attention controln = 76reference
Primary endpoint
Change in mean daily steps from baseline
Follow-up
Through the intervention period

Primary result

Change in mean daily steps · intervention period

Difference

+759 steps

95% CI 209–1,309

P = 0.007

As reported in the abstract

Further findings

OutcomeEstimateP value
Change in mean daily steps · follow-updifference +581 steps (95% CI −47 to 1,208)P = 0.070
Weekly minutes of moderate-vigorous physical activity · interventiondifference +16 minutes (95% CI 4–29)P = 0.010
Weekly minutes of moderate-vigorous physical activity · follow-updifference +11 minutes (95% CI 0–22)P = 0.048

Original publication

Behaviorally Designed Gamification and Physical Activity Among Breast and Prostate Cancer Survivors. JACC CardioOncol. Published 3 November 2025. doi:10.1016/j.jaccao.2025.10.001

Summarised from the published abstract; every number is checked against it