Coronary disease & ACSDiagnostic or prognostic study
Benchmarking Photon-Counting Computed Tomography Angiography Against Invasive Assessment of Coronary Stenosis
- Diagnostic accuracy study
Authors' conclusion
UHR-PCCTA luminal evaluation is superior to SR-PCCTA, especially in patients with heavy coronary calcification. UHR-PCCTA has excellent diagnostic performance in identifying coronary arteries with ≥50% luminal stenosis on 3D QCA, outperforming standard-resolution imaging.
Study context
- Population
- Patients who had both PCCTA and invasive coronary angiography257 vessels, 343 plaques analysed
- Participants
- 100 patients
- Comparison
- UHR-PCCTA vs SR-PCCTA vs 3D QCA
- Outcome
- Luminal diameter stenosis vs 3D QCA, CAD-RADS severity, and diagnostic performance for ≥50% diameter stenosis on 3D QCA
Performance
Luminal stenosis difference vs 3D QCA
ΔAUC
0.05
95% CI 0.01–0.08
P = 0.01
By group
As reported in the abstract
Further findings
| Outcome | P value |
|---|---|
| Severely calcified arteries (subgroup) | P = 0.002 |
Original publication
Benchmarking Photon-Counting Computed Tomography Angiography Against Invasive Assessment of Coronary Stenosis. JACC Cardiovasc Imaging. Published 11 February 2025. doi:10.1016/j.jcmg.2024.11.005
Summarised from the published abstract; every number is checked against it