Valvular & structural heart diseaseMechanistic study
Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves
- Mechanistic study
- in vitro bench study
- hydrodynamic assessment
- micro-CT imaging
Authors' conclusion
When performing VIV TAVR inside a Trifecta and Hancock SHV, BVR had a limited impact on THV expansion and resulted in SHV post flaring with unknown consequences on coronary obstruction risk and long-term THV function.
Study context
- Population
- Valve-in-valve (VIV) transcatheter aortic valve replacement (TAVR) in 21/23-mm Trifecta and 21/23-mm Hancock surgical heart valves, bioprosthetic valve remodeling (BVR) with a noncompliant TRUE balloon
- Comparison
- S3 vs Evolut Pro
- Outcome
- Impact of BVR of nonfracturable surgical heart valve (SHVs) on THV expansion and function after VIV implantation
Main finding
As reported in the abstract
THV expansion, SHV post flaring and hydrodynamic function after BVR
Largest gain in expansion: S3 in 21-mm Trifecta, outflow of the valve
up to a 12.7% increase
Surgical post flaring, generally more marked with S3 than Evolut Pro
up to 17.6°
Original publication
Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves. JACC Cardiovasc Interv. Published 7 June 2023. doi:10.1016/j.jcin.2023.03.035
Summarised from the published abstract; every number is checked against it