Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events : A Cohort Study
Authors' conclusion
Increasing BP levels in late adolescence are associated with gradually increasing risks for major cardiovascular events, beginning at a BP level of 120/80 mm Hg.
Study context
- Population
- Males in late adolescence conscripted into the military in Sweden, 1969–1997; mean age 18.3 years79,644 primary outcomes
- Participants
- 1,366,519 males
- Exposure
- Blood pressure (BP) categories in late adolescence vs normal BP
- Outcome
- CV death or first hospitalization for MI, HF, ischemic stroke or intracerebral hemorrhage
- Follow-up
- Median 35.9 years
Methodological detailsObservational study of Swedish men
- Observational study of Swedish men
Main finding
As reported in the abstract
Each group vs normal BPAdjusted hazard ratio (95% CI)
Elevated BP
1.10(1.07–1.13)
Stage 1 ISH
1.15(1.11–1.18)
Stage 1 IDH
1.23(1.18–1.28)
Stage 1 SDH
1.32(1.27–1.37)
Stage 2 ISH
1.31(1.28–1.35)
Stage 2 IDH
1.55(1.42–1.69)
Stage 2 SDH
1.71(1.58–1.84)
Observational data: associations, not effects.
Further findings
Cumulative risk of CV events · age 68 years
Cumulative risk of CV events · age 68 years
- Increased gradually across BP stages
Original publication
Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events : A Cohort Study. Ann Intern Med. Published 26 September 2023. doi:10.
Summarised from the published abstract; every number is checked against it