Heart failure & cardiomyopathies
Blood Pressure Levels and Adverse Cardiovascular Outcomes in Heart Failure: A Systematic Review and Meta-Analysis
Authors' conclusion
The findings suggest that lower and normal baseline SBP levels (<130, <120, and <110 mmHg) may be associated with future risk of worse outcomes in patients with HF. Optimal baseline blood pressure levels for these patients may lie within the range of ≥140 mmHg for SBP.
Study context
- Population
- Patients with heart failure (HF)
- Participants
- 120,643 patients43 cohort studies
- Comparison
- Higher vs lower SBP and DBP levels in HF
- Outcome
- Adverse CV events and all-cause mortality
Pooled result
As reported in the abstract
Relative risk (95% CI)
SBP ≥140 mmHgvs SBP <140 mmHgall-cause mortality
0.92(0.83–1.01)
SBP ≥140 mmHgvs SBP <140 mmHgCVD death
0.83(0.67–1.04)
SBP ≥140 mmHgvs SBP <140 mmHgHF hospitalization
0.98(0.80–1.21)
SBP ≥160 mmHgvs SBP <160 mmHgall-cause mortality
0.67(0.62–0.74)
DBP ≥80 mmHgvs DBP <80 mmHgall-cause mortality
0.86(0.67–1.10)
Original publication
Blood Pressure Levels and Adverse Cardiovascular Outcomes in Heart Failure: A Systematic Review and Meta-Analysis. Eur J Heart Fail. Published 25 January 2024. doi:10.
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