Heart failure & cardiomyopathiesMeta-analysis
Blood Pressure Levels and Adverse Cardiovascular Outcomes in Heart Failure: A Systematic Review and Meta-Analysis
- Systematic review and meta-analysis of observational cohort studies
Authors' conclusion
The findings suggest that lower and normal baseline SBP levels (<130, <120, and <110 mmHg) may be associated with future risk of worse outcomes in patients with HF. Optimal baseline blood pressure levels for these patients may lie within the range of ≥140 mmHg for SBP.
Study context
- Population
- Patients with heart failure (HF)
- Participants
- 120,643 patients · 43 cohort studies
- Comparison
- Higher vs lower SBP and DBP levels in HF
- Outcome
- Adverse CV events and all-cause mortality
Pooled result
As reported in the abstract
Relative risk (95% CI)
SBP ≥140 mmHg vs SBP <140 mmHgall-cause mortality
0.92(0.83–1.01)
SBP ≥140 mmHg vs SBP <140 mmHgCVD death
0.83(0.67–1.04)
SBP ≥140 mmHg vs SBP <140 mmHgHF hospitalization
0.98(0.80–1.21)
SBP ≥160 mmHg vs SBP <160 mmHgall-cause mortality
0.67(0.62–0.74)
DBP ≥80 mmHg vs DBP <80 mmHgall-cause mortality
0.86(0.67–1.10)
Original publication
Blood Pressure Levels and Adverse Cardiovascular Outcomes in Heart Failure: A Systematic Review and Meta-Analysis. Eur J Heart Fail. Published 25 January 2024. doi:10.1002/ejhf.3108
Summarised from the published abstract; every number is checked against it