HypertensionCross-sectional study

Blood pressure response to graded bicycle exercise in males and females across the age and fitness spectrum

Eur J Prev CardiolPublished

  • Cross-sectional study

Authors' conclusion

In a large cohort of healthy individuals, an exaggerated SBPmax was common and associated with higher fitness. In contrast, higher SBP indexed to W was associated with older age, lower fitness, and female sex.

Study context

Population
Healthy adults undergoing cardiopulmonary exercise testing with repeated automated blood pressure (BP) measures81% male
Participants
589 adults
Exposure
Males vs Females
Outcome
Normal exercise BP response (exaggerated SBPmax: ≥210 mmHg males, ≥190 mmHg females; SBP/W-slope) and its relationships with age, sex and fitness

Main finding

As reported in the abstract

Exaggerated SBPmax and SBP/W-slope

Exaggerated SBPmax and SBP/W-slope

Exaggerated SBPmax Males 51% · Females 64%

Exaggerated SBPmax, endurance-trained athletes Males 58% · Females 72%

  • Males vs Females: P = 0.031 — mean SBP/W-slope lower in males
Exaggerated SBPmax more prevalent in endurance-trained athletes
P < 0.001
VO2peak inversely correlated with SBP/W-slope in both sexes
P < 0.01
Exaggerated SBPmax with below-median SBP/W-slope: 10 years younger and 20% higher VO2peak on average
P < 0.001

Observational data: associations, not effects.

Original publication

Blood pressure response to graded bicycle exercise in males and females across the age and fitness spectrum. Eur J Prev Cardiol. Published 8 August 2024. doi:10.1093/eurjpc/zwae262

Summarised from the published abstract; every number is checked against it