HypertensionCohort study
Blood pressure status and risk of cardiovascular disease in older adults aged 75+ without prior cardiovascular events: a nationwide cohort study
- Retrospective cohort study
- nationwide
Authors' conclusion
In this large observational cohort, elevated blood pressure (BP) categories were associated with higher risks of stroke and myocardial infarction in adults aged ≥75 years, with the highest risk in uncontrolled hypertension. Stroke risk rose progressively with increasing systolic BP, whereas myocardial infarction demonstrated a U-shaped relationship with diastolic BP.
Study context
- Population
- Adults aged ≥75 years without prior cardiovascular disease (CVD) events undergoing health check-ups in 2012–2015, Korean National Health Insurance Service database
- Participants
- 869,781 adults
- Exposure
- Hypertension status categories vs normal blood pressure (BP)
- Outcome
- Incident CVD (stroke or MI)
- Follow-up
- Mean 6.67 years
Main finding
As reported in the abstract
Incident CVD
Each group vs normalHazard ratio (95% CI)
Pre-hypertension
1.13(1.11–1.16)
New-onset hypertension
1.29(1.26–1.33)
Controlled hypertension
1.21(1.18–1.23)
Uncontrolled hypertension
1.33(1.30–1.36)
- Participants developing CVD
- 120,353 (13.8%)
Observational data: associations, not effects.
Further findings
Stroke and MI
- Similar associative patterns observed for stroke and MI
Original publication
Blood pressure status and risk of cardiovascular disease in older adults aged 75+ without prior cardiovascular events: a nationwide cohort study. Eur J Prev Cardiol. Published 22 January 2026. doi:10.1093/eurjpc/zwag024
Summarised from the published abstract; every number is checked against it