Arrhythmias & electrophysiologyCohort study
Body mass index and pulmonary vein isolation: real-world data on outcomes and quality of life
- Prospective multicentre registry cohort study
- prospectively collected data
- 15 ablation centres
Authors' conclusion
Obesity is independently associated with a higher rate of repeat ablations. Pulmonary vein isolation is equally safe in all weight classes. Despite lower quality of life among obese individuals, substantial improvements occur for all weight groups after PVI.
Study context
- Population
- All first-time pulmonary vein isolation (PVI) patients in the Netherlands, 2015–2021
- Participants
- 20,725 patients
- Exposure
- Obesity vs overweight vs normal weight
- Outcome
- Repeat ablations
- Follow-up
- First year after PVI
Main finding
As reported in the abstract
Odds ratio
1.15
95% CI 1.01–1.31
P = 0.03
By group
Obesity
17.8
%
Normal weight
15.6
%
Overweight
16.1%
Obesity vs Normal weight
OR 1.15 (95% CI 1.01–1.31); P = 0.03
- Obese vs normal-weight and overweight
- P < 0.05
Observational data: associations, not effects.
Further findings
Repeat ablations · 3 years
- Association with obesity remained apparent
Quality of life (AFEQT) · 1 year post-PVI
- Improved in all weight groups but remained lowest in obese patients
Safety
Complications
Complications
- Weight class not an independent predictor
Original publication
Body mass index and pulmonary vein isolation: real-world data on outcomes and quality of life. Europace. Published 13 June 2024. doi:10.1093/europace/euae157
Summarised from the published abstract; every number is checked against it