Arrhythmias & electrophysiologyResearch article

Ca2+ signalling in cardiac muscle: the importance of balances

EuropacePublished

  • Narrative review

Study context

Population
Catecholaminergic polymorphic VT from a point mutation of the cardiac ryanodine receptor (RyR2R420Q phenotype)

Main finding

As reported in the abstract

Molecular and cellular pathomechanism of CPVT from the RyR2R420Q point mutation of the cardiac ryanodine receptor
  • RyR2R420Q findings and conclusions were very much unexpected but could be relevant for pharmacological treatments
  • narrative review

Original publication

Ca2+ signalling in cardiac muscle: the importance of balances. Europace. Published 13 March 2026. doi:10.1093/europace/euag038

Summarised from the published abstract; every number is checked against it