Prevention & lipidsCohort study
Can incidental physical activity offset the deleterious associations of sedentary behaviour with major adverse cardiovascular events?
- Prospective cohort study
- UK Biobank accelerometry sub-study
- tertile-based joint associations
Authors' conclusion
Brief intermittent bursts of vigorous incidental physical activity may offset cardiovascular risks from high sedentary behaviour.
Study context
- Population
- Non-exercising adults, UK Biobank accelerometry sub-study (median age 62.9 years; 41.8% male)819 major adverse cardiovascular events (MACE) events
- Participants
- 22,368 adults
- Exposure
- Joint categories of incidental physical activity and sedentary behaviour
- Outcome
- MACE
- Follow-up
- 8.0-year median
Main finding
As reported in the abstract
Each group vs highest physical activity, lowest sedentary timeHazard ratio (95% CI)
High sedentary, low incidental VPA
1.34(0.98–1.84)
High sedentary, low incidental MVPA
1.89(1.42–2.52)
- VPA or vigorous intermittent lifestyle physical activity (VILPA) that may offset MACE risk of high sedentary behaviour
- 4.1 min/day
- Incidental MVPA largely attenuating associations with MACE
- 31-65 min
- Moderate to vigorous intermittent lifestyle physical activity (MV-ILPA) per day largely attenuating associations with MACE
- 26-52 min
Observational data: associations, not effects.
Original publication
Can incidental physical activity offset the deleterious associations of sedentary behaviour with major adverse cardiovascular events? Eur J Prev Cardiol. Published 26 September 2024. doi:10.1093/eurjpc/zwae316
Summarised from the published abstract; every number is checked against it