Valvular & structural heart disease

Cardiac implantable electronic device implantation and function after transcatheter tricuspid valve replacement

Heart RhythmPublished Observational cohort study

Authors' conclusion

After TTVR, bradyarrhythmias necessitating pacemaker implantation were common, and CIED implantation, mainly consisting of leadless pacemaker implantation, was successful in all cases. In patients with preexisting CIEDs, all TTVR procedures were performed successfully, though lead-related complications did occur.

Study context

Population
Patients undergoing transcatheter tricuspid valve replacement (TTVR)
Participants
Sixty-three patients
Exposure
TTVR in patients with vs without existing cardiac implantable electronic devices (CIEDs)
  • No CIEDn = 42
  • Existing CIEDn = 21
Outcome
CIED outcomes after TTVR: incidence of bradyarrhythmias and pacemaker implantation, and outcomes with preexisting CIEDs

Main finding

As reported in the abstract

Bradyarrhythmias requiring pacemaker implantation (no CIED)

No CIED

30.1%

13

Leadless pacemakers implanted successfully
13
Tricuspid valve sparing transvenous pacemaker implanted successfully
1

Observational data: associations, not effects.

Further findings

Outcomes with existing CIED · postprocedurally and at short-term follow-up

Remaining devices had normal function; all TTVR procedures with "jailed" leads performed successfully

Safety

Patients with an RV pacing lead with acute lead dislodgment requiring leadless pacemaker
1
Remaining devices: normal function postprocedurally and at short-term follow-up

Original publication

Cardiac implantable electronic device implantation and function after transcatheter tricuspid valve replacement. Heart Rhythm. Published 5 August 2025. doi:10.1016/j.hrthm.2025.07.049

Summarised from the published abstract; every number is checked against it

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