Arrhythmias & electrophysiology
Cardiac magnetic resonance to evaluate 3-dimensional ventricular substrate depth: Prognostic implications for ventricular tachycardia ablation approach
Authors' conclusion
In patients with left-scar-related VT, the maximal depth of CMR channels predicts VT recurrence after endocardial ablation.
Study context
- Population
- Patients with left-scar-related ventricular tachycardia (VT) undergoing exclusive endocardial ablation after cardiac magnetic resonance (CMR) (72.5% ischemic cardiomyopathy)159 CMR channels analysed
- Participants
- 51 patients
- Exposure
- CMR channel depth and epicardial channel presence as predictors of VT recurrence after endocardial ablation
- Outcome
- VT recurrence
Methodological detailssingle-centre, consecutive patients, Hospital Clinic, October 2018 to June 2022
- Single-centre
- Consecutive patients
- Hospital Clinic, October 2018 to June 2022
Main finding
As reported in the abstract
| Group | OR (univariable) | Cutoff | Sensitivity | Specificity | NPV | AUC | PPV |
|---|---|---|---|---|---|---|---|
| Maximal channel depth | 1.85 [1.11-3.13], P = .02 | 7.2 mm | 100% | 61.4% | 100% | 0.81 | |
| Epicardial channel | 1.22 [1.15-1.41], P = .04 | 100% | 27.27% | 100% | 17.95% |
OR (univariable)
Maximal channel depth1.85 [1.11-3.13], P = .02
Epicardial channel1.22 [1.15-1.41], P = .04
Cutoff
Maximal channel depth7.2 mm
Epicardial channel— not stated in the abstract
Sensitivity
Maximal channel depth100%
Epicardial channel100%
Specificity
Maximal channel depth61.4%
Epicardial channel27.27%
NPV
Maximal channel depth100%
Epicardial channel100%
AUC
Maximal channel depth0.81
Epicardial channel— not stated in the abstract
PPV
Maximal channel depth— not stated in the abstract
Epicardial channel17.95%
Observational data: associations, not effects.
Further findings
- 1-year VT recurrence rate
- 13.7%
Original publication
Cardiac magnetic resonance to evaluate 3-dimensional ventricular substrate depth: Prognostic implications for ventricular tachycardia ablation approach. Heart Rhythm. Published 6 November 2025. doi:10.
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