Valvular & structural heart diseaseResearch article
Cardiac Structural Complications Following TAVR
- Multicenter study
- consecutive patients
- 18 European and Canadian centers
- 2014 to 2024
Authors' conclusion
About 2% of contemporary transcatheter aortic valve replacement recipients presented CSCs, which did not decrease over time, required conversion to surgery in more than one-fourth of cases, and were associated with very high periprocedural mortality rates. Further research is needed regarding potential preventive strategies and optimal surgical bailout management.
Study context
- Population
- Consecutive patients undergoing transcatheter aortic valve replacement
- Participants
- 10,541 total patients
Main finding
As reported in the abstract
CSCs incidence
- Cardiac structural complications (CSCs)
- 221 (2.1%)
- patients exhibiting >1 CSC
- 126 (1.2%)
- cardiac structure compromise events
- 146 (1.4%)
- annular rupture (of cardiac structure compromise events)
- 41.1%
- left ventricular perforation (of cardiac structure compromise events)
- 26.0%
- right ventricular perforation (of cardiac structure compromise events)
- 24.0%
- other injuries (of cardiac structure compromise events)
- 8.9%
- new pericardial effusions
- 150 (1.4%)
- coronary obstructions
- 59 (0.6%)
Further findings
Timing and management of CSCs
- CSCs occurring intraprocedurally
- Up to 75.6%
- patients with CSCs who had conversion to open heart surgery
- 61 (27.6%)
Incidence of CSCs over study period
- range
- from 1.3% to 3.2%
- median annual rate
- 2.3%
- remained similar throughout the study period
Mortality among patients with CSCs · 30 days
- Thirty-day mortality
- 35.3%
- among patients requiring conversion to surgery
- 52.5%
- annular rupture
- 41.0%
Original publication
Cardiac Structural Complications Following TAVR. Circ Cardiovasc Interv. Published 5 February 2026. doi:10.1161/circinterventions.125.015991
Summarised from the published abstract; every number is checked against it