Acute cardiac care & resuscitation

Cardiogenic Shock With Acute Myocardial Infarction Among Older Adults in the United States

JACC AdvPublished National Inpatient Sample database

Authors' conclusion

From 2003 to 2021, for older patients with CS and AMI, hospitalizations increased, and mortality decreased.

Study context

Population
Hospitalizations of older patients ≥80 years with cardiogenic shock (CS) and acute myocardial infarction (AMI) from 2003 to 2021, compared with a reference relatively younger patient population (18–79 years)hospitalizations · older patients ≥80 years 207,333 · patients 18 to 79 years 675,491
Participants
207,333 vs 675,491
Exposure
Older patients with a reference relatively younger patient population
  • Older patients ≥80 yearsn = 207,333
  • Patients 18 to 79 yearsn = 675,491
Outcome
Number of hospitalizations of older patients with AMI and CS
Follow-up
2003-2006 vs 2016-2019

Main finding

As reported in the abstract

Increase in the number of hospitalizations

39,220-51,640

Observational data: associations, not effects.

Further findings

In-hospital mortality · greater in-hospital mortality with aged ≥80 years

P < 0.001

Percentage of older patients undergoing treatment with percutaneous coronary intervention · over the study period

Increase
19.2% to 34.1%; P < 0.001
  • Adjusted analysis

Encounters for palliative care (older patients) · over the study period

Increase
2.0% to 32.4%; P < 0.001
  • Adjusted analysis

In-hospital mortality (older patients) · over the study period

Decline
61.4% to 49.0%; P < 0.001
  • Adjusted analysis

Original publication

Cardiogenic Shock With Acute Myocardial Infarction Among Older Adults in the United States. JACC Adv. Published 19 August 2025. doi:10.1016/j.jacadv.2025.102078

Summarised from the published abstract; every number is checked against it

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