Prevention & lipidsCohort study
Cardiovascular disease risk among young adults with disabilities: a nationwide cohort study
- Retrospective cohort study
- nationwide
- exact-matched 1:10
Authors' conclusion
In young adults, disability is associated with higher incident CVD risk independent of conventional risk factors, with heterogeneity by type and severity- and duration-related gradients.
Study context
- Population
- Korean adults aged 20–39 years without prior cardiovascular disease (CVD) undergoing national health screening (2009–2014)7,925 developed CVD
- Participants
- 7,682,700 adults
- Exposure
- Disability vs no disability
- Disabilitiesn = 91,500
- Outcome
- Composite of:
- Hospitalisation for MI
- Stroke
- HF
- CV death
- Follow-up
- Median 11 years
Main finding
Incident CVD
Hazard ratio
1.34
95% CI 1.25–1.44
By group
Disabilities vs Matched controls
HR 1.34 (95% CI 1.25–1.44)
As reported in the abstract
Observational data: associations, not effects.
Further findings
CVD risk by disability type, severity and duration
- Risk varied by disability type (highest for brain lesion-related disability)
- Risk increased with greater severity
- Risk increased gradually with longer disability duration
Original publication
Cardiovascular disease risk among young adults with disabilities: a nationwide cohort study. Eur J Prev Cardiol. Published 10 June 2026. doi:10.1093/eurjpc/zwag321
Summarised from the published abstract; every number is checked against it