Prevention & lipidsMeta-analysis

Cardiovascular Disease Screening Programs in Low- and Middle-Income Countries

JACC AdvPublished

  • systematic review
  • in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines
  • results synthesized narratively

Authors' conclusion

CVD screening programs in LMICs can effectively identify unmet cardiometabolic risk, but weak linkage to care limits impact. Strengthening integrated screening-to-treatment pathways is essential to improve outcomes.

Study context

Population
Observational and interventional studies assessing cardiovascular or major cardiometabolic screening programs in low- and middle-income countries (LMICs)studies from Asia, sub-Saharan Africa, and Latin America
Participants
Seventeen participants
Outcome
Detection rates and linkage to care

Pooled result

As reported in the abstract

Meeting hypertension criteria

up to 55%

Classified as high risk for diabetes

approximately 40%

Preventive service uptake

15% to 58%

Confirmatory testing

as low as 22%

Further pooled results

Diagnostic performance

Area under the curve range
0.64 to 0.91
Locally adapted risk models generally outperformed imported scores, whereas simplified tools showed acceptable discrimination

Community health worker-led programs vs clinician assessment

Sensitivity and specificity
>90%

Original publication

Cardiovascular Disease Screening Programs in Low- and Middle-Income Countries. JACC Adv. Published 22 July 2026. doi:10.1016/j.jacadv.2026.103048

Summarised from the published abstract; every number is checked against it