Cardiovascular disease-specific and all-cause mortality across socioeconomic status and lifestyles among patients with established cardiovascular disease in communities of China: data from a national population-based cohort
Study context
- Population
- Adults aged 35–75 years with self-reported CVD in communities of China, September 2014 to March 20215,010 deaths
- Participants
- 104,718 adults
- Exposure
- Low and medium socioeconomic status (SES) vs high SES
- High SESn = 27,943reference
- Medium SESn = 35,802
- Low SESn = 40,973
- Outcome
- All-cause and CVD mortality
- Follow-up
- Mean 48.9±18.9 months
Methodological detailsnationwide population-based, 31 provinces of Chinese mainland
- Nationwide population-based
- 31 provinces of Chinese mainland
Main finding
As reported in the abstract
Low SES vs High SESHazard ratio (95% CI)
All-cause death
1.65(1.50–1.80)
CVD death
1.95(1.72–2.20)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Low SES with worst lifestyle vs high SES with healthy lifestyleLow SES, worst lifestylevs High SES, healthy lifestyleAll-cause mortality | 2.72 (2.37–3.12) | |
| Low SES with worst lifestyle vs high SES with healthy lifestyleLow SES, worst lifestylevs High SES, healthy lifestyleCVD mortality | 3.18 (2.64–3.83) | |
| 0.20.5125Hazard ratio (log scale) |
Joint mediation by lifestyles of excess CVD mortality in low SES
- Proportion mediated
- 19.6% (95% CI 14.8% to 24.2%)
- Strongest mediator leisure-time physical activity, then dietary factors
- All-cause mortality: similar
- Interaction P by gender = 0.013
- Interaction P by urbanity = 0.004
Original publication
Cardiovascular disease-specific and all-cause mortality across socioeconomic status and lifestyles among patients with established cardiovascular disease in communities of China: data from a national population-based cohort. Heart. Published 13 March 2025. doi:10. 1136/ heartjnl-2024-324766
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