Coronary disease & ACSCross-sectional study
Cardiovascular hospitalizations and mortality among adults aged 25–64 years in the USA
- Repeated cross-sectional study
- National Inpatient Sample
- age-standardized rates
Authors' conclusion
There was an alarming increase in cardiovascular hospitalizations among younger adults in the USA from 2008 to 2019, and disparities between those residing in low- and higher-income communities did not narrow.
Study context
- Population
- US adults aged 25–64 years hospitalized for acute myocardial infarction (AMI), HF or ischaemic stroke, 2008–2019
- Exposure
- Low-income vs higher-income communities; 2019 vs 2008
- Outcome
- Age-standardized annual hospitalization and in-hospital mortality rates for AMI, HF and ischaemic stroke
- Follow-up
- 2008–2019
Main finding
As reported in the abstract
Age-standardized hospitalization rates (per 100 000), adults aged 25-64 years · 2008 to 2019
2008
155.0 (95% CI 154.6, 155.4)
AMI · HF 165.3 [164.8, 165.7] · Ischaemic stroke 76.3 [76.1, 76.7]
2019
160.7 (160.3, 161.1)
AMI · HF 225.3 [224.8, 225.8] · Ischaemic stroke 108.1 [107.8, 108.5]
- 2019 vs 2008 · AMI hospitalizations
- absolute change +5.7 per 100 000 (CI 5.0–6.3); P < 0.001
- Heart failure hospitalizations · increase over study period
- absolute change +60.0 (CI 59.3–60.6); P < 0.001
- ischaemic stroke hospitalizations · increase over study period
- absolute change +31.7 (CI 31.2–32.2); P < 0.001
Observational data: associations, not effects.
Further findings
Hospitalization rates by community income
- Significantly higher in low-income vs higher-income communities across all conditions; disparities did not narrow
In-hospital mortality · 2008–2019
- Decreased for all conditions over the study period
Original publication
Cardiovascular hospitalizations and mortality among adults aged 25–64 years in the USA. Eur Heart J. Published 11 November 2023. doi:10.1093/eurheartj/ehad772
Summarised from the published abstract; every number is checked against it