Heart failure & cardiomyopathiesCross-sectional study

Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium

JACC Cardiovasc ImagingPublished

  • Cross-sectional study
  • international collaborative
  • multi-vendor

Analysed with cvi42 (version 5.14 prototype) by 2 expert readers; 3 segmentation methods (smooth, papillary, anatomic)

Authors' conclusion

This work represents a resource with healthy CMR-derived volumetric reference ranges ready for clinical implementation.

Study context

Population
Verified healthy adults (18–83 years), Healthy Hearts ConsortiumCardiovascular magnetic resonance (CMR) studies
Participants
9,088 adults
Outcome
Age-, sex- and ethnicity-specific CMR reference ranges for atrial and ventricular metrics (95% prediction intervals)

Main finding

As reported in the abstract

Men
4,452 (49.0%)
Women
4,636 (51.0%)
Age, mean ± SD (range 18-83 years)
61.1 ± 12.9 years
White
7,424 (81.7%)
South Asian
510 (5.6%)
Mixed/other
478 (5.3%)
Black
341 (3.7%)
Chinese
335 (3.7%)
1.5-T scanners
8,779; 96.6%
3.0-T scanners
309; 3.4%
Siemens
8,299; 91.3%
Philips
498; 5.5%
GE
291, 3.2%

Observational data: associations, not effects.

Original publication

Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium. JACC Cardiovasc Imaging. Published 10 April 2024. doi:10.1016/j.jcmg.2024.01.009

Summarised from the published abstract; every number is checked against it