Prevention & lipidsCohort study

Cardiovascular risk assessment in male and female patients with and without depression: an electronic health record evaluation in Wales

Eur J Prev CardiolPublished

  • Retrospective cohort study
  • electronic health record data

Authors' conclusion

Patients with depression are more likely to have their blood pressure, lipid levels and QRISK documented than patients without depression.

Study context

Population
Primary care patients in Wales, primary prevention of cardiovascular disease (CVD)
Participants
2,290,075 patients
Exposure
Depression vs no depression
  • Depressionn = 176,062
Outcome
Rates of CV risk factor assessment (BP measurement, lipid checks, QRISK documentation)

Main finding

As reported in the abstract

BP, lipid and QRISK assessment
  • Patients with depression had BP and lipid levels checked and QRISK score documented more frequently (adjusted for sex and age group)
  • Poisson regression adjusted for age and sex

Observational data: associations, not effects.

Further findings

Sex differences in assessment

Younger females more likely to have BP assessment; males more likely to have lipid levels checked, irrespective of depression status
Significant three-way interactions depression*sex*age group for all outcomes; sex/depression difference in lipid assessment most notable in 60-74 age group

Original publication

Cardiovascular risk assessment in male and female patients with and without depression: an electronic health record evaluation in Wales. Eur J Prev Cardiol. Published 26 March 2025. doi:10.1093/eurjpc/zwaf178

Summarised from the published abstract; every number is checked against it