Prevention & lipids

Cardiovascular Risk, Health Metrics, and Cancer Prediction: A Scoping Review

JACC CardioOncolPublished Systematic review of prospective studies

Authors' conclusion

Despite heterogeneity in CVD risk metrics and cancer types, most studies suggested that worse CVD risk scores or CVH metrics predict greater cancer risk.

Study context

Population
Adults aged ≥18 years in prospective studies of cardiovascular disease (CVD) risk scores or cardiovascular health (CVH) metrics and cancer incidence13 studies
Comparison
CVD risk scores and CVH metrics as predictors of incident cancer
Outcome
Incident cancer

Pooled result

As reported in the abstract

Higher CVD risk scores consistently associated with increased cancer risk (HRs)

1.16-3.71

Ideal CVH metrics associated with reduced cancer risk (HRs)

0.49-0.95

Original publication

Cardiovascular Risk, Health Metrics, and Cancer Prediction: A Scoping Review. JACC CardioOncol. Published 15 July 2025. doi:10.1016/j.jaccao.2025.05.011

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