Pulmonary vascular disease & thromboembolismCohort study

Catheter-based therapy for high-risk or intermediate-risk pulmonary embolism: death and re-hospitalization

Eur Heart JPublished

  • Retrospective cohort study
  • Inverse probability of treatment weighting (IPTW)
  • National Readmission Database 2017-20

Authors' conclusion

Among patients with high-risk or intermediate-risk PE, CBT was associated with lower in-hospital death and 90-day readmission.

Study context

Population
Patients hospitalized with intermediate-risk or high-risk PE14,903 high-risk
Exposure
CBT vs no CBT
Outcome
In-hospital death
Follow-up
In-hospital

Main finding

As reported in the abstract

CBT vs No CBTOdds ratio (95% CI)
high-risk PE
0.83(0.80–0.87)
intermediate-risk PE
0.76(0.70–0.83)

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
90-day all-cause readmission · 90 days — CBT vs No CBT · high-risk PE0.77 (0.71–0.83)
90-day all-cause readmission · 90 days — CBT vs No CBT · intermediate-risk PE0.75 (0.72–0.79)
90-day VTE readmission · 90 days — CBT vs No CBT · high-risk PE0.46 (0.34–0.63)
90-day VTE readmission · 90 days — CBT vs No CBT · intermediate-risk PE0.66 (0.57–0.76)

Original publication

Catheter-based therapy for high-risk or intermediate-risk pulmonary embolism: death and re-hospitalization. Eur Heart J. Published 4 April 2024. doi:10.1093/eurheartj/ehae184

Summarised from the published abstract; every number is checked against it