Heart failure & cardiomyopathiesRandomised controlled trial

Center- vs Home-Based Cardiac Rehabilitation in Patients With Heart Failure

JACC Heart FailPublished

  • Randomised controlled trial
  • single-centre
  • parallel group
  • non-inferiority

Authors' conclusion

In a contemporary well-treated HF population, home-based CR was noninferior to the center-based program

Study context

Population
Heart failure (HF) patients irrespective of EF95 (79%) with complete Vo2peak data
Participants
120 patients
Comparison
Home-based vs centre-based cardiac rehabilitation
  • Center-basedn = 45reference
  • Home-basedn = 75
Primary endpoint
Change in peak oxygen uptake (Vo2peak)
Follow-up
12 weeks

Primary result

As reported in the abstract

Change in Vo2peak from baseline to week 12

No significant between-group difference in Vo2peak change (between-group difference 0.8 mL/kg/min, 95% CI 1.8 to −0.16 mL/kg/min)

P = 0.10

Secondary outcomes

Exercise adherence to the CR program · similar between groups

6-minute walking distance, Minnesota Living with HF Questionnaire, disease-related biomarkers, physical fitness

No between-group differences

Original publication

Center- vs Home-Based Cardiac Rehabilitation in Patients With Heart Failure. JACC Heart Fail. Published 29 January 2025. doi:10.1016/j.jchf.2024.09.024

Summarised from the published abstract; every number is checked against it