Changes in Cardiovascular Health at Midlife and Subsequent Cardiovascular Outcomes in Individuals With Diabetes
Authors' conclusion
For patients with diabetes, achieving or maintaining ideal CVH levels at midlife may help improve outcome; however, CVD risk is not completely mitigated by favorable CVH trajectories.
Study context
- Population
- Midlife adults with and without diabetes, ARIC Study; median follow-up 23 years806 with diabetes (9.2%)
- Participants
- 8,741 adults
- Exposure
- Change in cardiovascular health (CVH) between visits 1 and 3 in individuals with diabetes
- Outcome
- CVD events and all-cause mortality
- Follow-up
- Median 23 years
Methodological detailsAtherosclerosis Risk in Communities Study, Cox proportional hazards regression
- Atherosclerosis Risk in Communities Study
- Cox proportional hazards regression
Main finding
As reported in the abstract
CVD events (individuals with diabetes)
Hazard ratio (95% CI)
Improved CVH
0.69(0.50–0.93)
Maintained moderate CVH
0.68(0.50–0.94)
Moderate to low CVH
0.60(0.41–0.88)
Observational data: associations, not effects.
Further findings
All-cause mortality (individuals with diabetes)
- Similar patterns as for cardiovascular disease (CVD) events
CVD events and mortality, diabetes vs no diabetes with maintained favorable CVH
- Those with diabetes consistently had higher risks regardless of CVH trajectory
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Changes in Cardiovascular Health at Midlife and Subsequent Cardiovascular Outcomes in Individuals With Diabetes. JACC Adv. Published 16 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →