Arrhythmias & electrophysiology

Characteristics and Management of Patients With Cancer and Atrial Fibrillation: The BLITZ-AF Cancer Registry

JACC AdvPublished Prospective observational registry study

Authors' conclusion

This study demonstrates that there is underuse of appropriate antithrombotic therapy for AF in cancer patients

Study context

Population
Patients with a recent cancer diagnosis and ECG-confirmed atrial fibrillation (AF)enrolled June 2019–September 2021
Participants
1,514 patients
Outcome
Clinical characteristics and contemporary management, with focus on antithrombotic treatments
Methodological detailsmulticentre, BLITZ-AF Cancer Registry
  • Multicentre
  • BLITZ-AF Cancer Registry

Main finding

As reported in the abstract

Antithrombotic therapy before admission/cardiologist consultation vs at discharge/after cardiologic assessment

No antithrombotic therapy, before

16.6%

No antithrombotic therapy, after

7.7%

Antiplatelet agents and/or low-molecular-weight heparin, before

22.7%

Antiplatelet agents and/or low-molecular-weight heparin, after

16.6%

Observational data: associations, not effects.

Further findings

Baseline characteristics

Mean age (years)
74 ± 9
Age >75 years
47.5%
Males
63.5%
HF
20.9%
CAD
18.1%
Valvular heart disease
38.5%
PAD
9.8%
Previous thromboembolic events
13.9%
Previous hemorrhagic events
10.4%
CHA2DS2VASc score ≥4
41.5%

Most common cancer types

Lung
14.9%
Colorectal
14.1%
Prostate
8.8%
Non-Hodgkin lymphoma
8.1%

Original publication

Characteristics and Management of Patients With Cancer and Atrial Fibrillation: The BLITZ-AF Cancer Registry. JACC Adv. Published 24 May 2024. doi:10.1016/j.jacadv.2024.100991

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