Valvular & structural heart diseaseCohort study
Characteristics and Outcomes of Patients with Atrial Versus Ventricular Secondary Tricuspid Regurgitation Undergoing Tricuspid Transcatheter Edge-to-Edge Repair – Results from the TriValve Registry
- Registry-based cohort study
- multicentre
- real-world registry
Authors' conclusion
In a real-world, multicentre registry, T-TEER was effective in reducing TR grade in both ASTR and VSTR. At 12-month follow-up, ASTR showed better survival than VSTR.
Study context
- Population
- Patients with secondary tricuspid regurgitation undergoing tricuspid transcatheter edge-to-edge repair, TriValve registry; primary tricuspid regurgitation (TR) and cardiac implantable electronic device excluded
- Participants
- 298 patients
- Exposure
- Atrial vs ventricular secondary TR undergoing tricuspid transcatheter edge-to-edge repair (T-TEER)
- Atrial STR (ASTR)n = 65
- Ventricular STR (VSTR)n = 233reference
- Outcome
- Procedural success and survival (key endpoints)
Main finding
As reported in the abstract
Procedural success
P = 0.56
Observational data: associations, not effects.
Further findings
Survival · 12 months
log-rank p = 0.02
TR ≥3+ after T-TEER (baseline 97% of patients)
- Survival — VSTR independent predictor of mortality (multivariable), HR
- 4.75
- TR ≥3+ after T-TEER (baseline 97% of patients): reduction from baseline, all p = 0.001
Original publication
Characteristics and Outcomes of Patients with Atrial Versus Ventricular Secondary Tricuspid Regurgitation Undergoing Tricuspid Transcatheter Edge-to-Edge Repair – Results from the TriValve Registry. Eur J Heart Fail. Published 8 November 2023. doi:10.1002/ejhf.3075
Summarised from the published abstract; every number is checked against it