Heart failure & cardiomyopathies
Characteristics and Outcomes of Patients with Cancer Hospitalized with New Onset Acute Heart Failure
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 1.40 99% CI 1.34–1.46Authors' conclusion
Cancer is a prevalent comorbidity in patients hospitalized with new onset AHF, and it is associated with a poorer prognosis.
Study context
- Population
- Adults hospitalized with first episode of acute HF, Lombardy, Italy, 2003–2018
- Participants
- 283,144 acute heart failure (AHF) hospitalizations
- Exposure
- Cancer vs no cancer history
- Cancern = 55,145
- Outcome
- In-hospital mortality
Methodological detailsadministrative data, Lombardy, Italy
- Administrative data
- Lombardy, Italy
Main finding
As reported in the abstract
Odds ratio
1.40
99% CI 1.34–1.46
By group
Cancer vs No cancer
OR 1.40 (99% CI 1.34–1.46)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Cancer | No cancer | Estimate | |
|---|---|---|---|---|
| All-cause mortality · 1 yearAdjusted; particularly lung cancer | 34.9% | 22.3% | HR 1.35 (99% CI 1.32–1.39) | |
| In-hospital mortality, active vs past cancer (subgroup)Similar risk | OR 0.99 (99% CI 0.91–1.07) | |||
| All-cause mortality, active vs past cancer (subgroup) · 1 year | HR 1.26 (99% CI 1.21–1.31) | |||
| 0.512Ratio (log scale) |
- All-cause mortality: unadjusted P < 0.0001
Original publication
Characteristics and Outcomes of Patients with Cancer Hospitalized with New Onset Acute Heart Failure. ESC Heart Fail. Published 16 October 2024. doi:10.
Summarised from the published abstract; every number is checked against it