Acute cardiac care & resuscitationCohort study
Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock
- retrospective analysis of the National Readmissions Database
Authors' conclusion
Patients with DM, particularly T1DM, who present with CS represent a high-risk cohort with greater in-hospital mortality and higher readmission rates compared to patients without DM.
Study context
- Population
- Patients hospitalized with any discharge diagnosis of cardiogenic shock (CS), 2016–2021patients hospitalized with CS · no diabetes mellitus (DM) 644,768 (60.0%) · T1DM 10,423 (1.0%) · T2DM 418,149 (39.0%)
- Participants
- 1,073,340 patients
- Exposure
- patients with no diabetes mellitus (DM), type 1 DM (T1DM), and type 2 DM (T2DM) admitted with CS
- CS without DMn = 644,768reference
- CS with T1DMn = 10,423
- CS with T2DMn = 418,149
- Outcome
- All-cause in-hospital mortality and 30-day readmissions
Main finding
As reported in the abstract
Each group vs CS without DMAdjusted odds ratio (95% CI)
CS with T1DM
1.16(1.09–1.24)
CS with T2DM
1.08(1.07–1.10)
Observational data: associations, not effects.
Further findings
Presentation and management
- T1DM more likely to present with CS due to acute myocardial infarction and undergo left heart catheterization compared to T2DM and no DM
In-hospital mortality in CS from acute myocardial infarction (subgroup)
- Similar between T1DM and no DM, but higher in T2DM
Original publication
Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock. JACC Adv. Published 28 April 2026. doi:10.1016/j.jacadv.2026.102766
Summarised from the published abstract; every number is checked against it