Valvular & structural heart diseaseCohort study
Characteristics, Trends, and Outcomes of Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Replacement in United States
- Retrospective cohort study
- propensity-score matched (3:1)
Authors' conclusion
In the United States, IVL is increasingly adopted to facilitate TF TAVR. IVL TAVR patients exhibited a higher burden of comorbidities and experienced more complications compared to non-IVL TAVR patients.
Study context
- Population
- Patients undergoing percutaneous transcatheter aortic valve replacement (TAVR), Vizient Clinical Database, US, October 2020–November 2023
- Participants
- 129,655 patients · 361 hospitals
- Exposure
- Intravascular lithotripsy (IVL) TAVR vs non-IVL TAVR
- IVL TAVRn = 1,242
- Outcome
- Composite of:
- In-hospital death
- Stroke
- Vascular complications
- Surgical vascular intervention
- Major bleeding
- Follow-up
- In-hospital
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Median
| Outcome | IVL TAVR | non-IVL TAVR |
|---|---|---|
| Elixhauser comorbidity score | 5 (IQR 4–7) | 4 (IQR 3–6) |
- TAVR completed via transfemoral (TF) approach (IVL TAVR)
- 99.7% · 1,238 of 1,242
In-hospital death and stroke
- Similar in both groups
Original publication
Characteristics, Trends, and Outcomes of Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Replacement in United States. JACC Cardiovasc Interv. Published 28 October 2024. doi:10.1016/j.jcin.2024.08.033
Summarised from the published abstract; every number is checked against it