Prevention & lipidsCohort study
Childhood exposure to multiple types of violence and adult cardiovascular disease
- Prospective cohort study
- population-based
Authors' conclusion
Childhood exposure to violence from parents, siblings, and peers is associated with an elevated risk of adult-onset CVD.
Study context
- Population
- Middle-aged and older adults in the China Health and Retirement Longitudinal Study (CHARLS); mean (SD) age 58 (9) years, 49.3% men
- Participants
- 11,398 participants
- Exposure
- Frequent childhood exposure to violence vs none
- Parentsn = 623
- Siblingsn = 117
- Peersn = 515
- Any typen = 1,101
- Outcome
- Self-reported, physician-diagnosed CVD
Main finding
As reported in the abstract
CVD
Hazard ratio (95% CI)
Parents
1.23(1.04–1.45)
Siblings
1.24(0.87–1.75)
Peers
1.25(1.05–1.49)
Any type
1.22(1.06–1.40)
Observational data: associations, not effects.
Further findings
Mediation by adult depressive symptoms (CES-D 10)
- Proportion of association between frequent violence exposure and cardiovascular disease (CVD) mediated
- 23.0%
- P for mediation
- P = 0.03
Subgroup and sensitivity analyses
- Associations consistent across subgroups and multiple sensitivity analyses
Original publication
Childhood exposure to multiple types of violence and adult cardiovascular disease. Eur J Prev Cardiol. Published 20 May 2025. doi:10.1093/eurjpc/zwaf292
Summarised from the published abstract; every number is checked against it