Cardiometabolic & kidneyCohort study

Chronic Kidney Disease Screening in Patients With Coronary Heart Disease

J Am Coll CardiolPublished

  • Prospective cohort study
  • 14 countries, all WHO regions

Authors' conclusion

Without UACR, half of those with CKD would remain undetected.

Study context

Population
Patients with coronary artery disease (CAD), assessed for estimated glomerular filtration rate (eGFR) and urinary albumin/creatinine ratio (UACR) 6 to 24 months after diagnosis (79.6% male; age 18–80 years)3,865 with complete data
Participants
4,548 patients
Exposure
low-moderate vs high vs very high risk
Outcome
First of CV death, MI, stroke, and hospitalization for HF
Follow-up
Median 1 year

Main finding

As reported in the abstract

CKD prevalence by KDIGO risk class
Chronic kidney disease (CKD) (KDIGO) present
32%
CKD undetected without UACR
51.3%

Observational data: associations, not effects.

Further findings

Outcomelow-moderatehighvery high risk
Primary event (CV death, MI, stroke, HF hospitalisation) · median 1 year
menNot reported in the abstract13.0%Not reported in the abstract
womenNot reported in the abstract11.8%Not reported in the abstract
Primary event (CV death, MI, stroke, HF hospitalisation) — Primary event, overall
7.9%

Primary event (CV death, MI, stroke, HF hospitalisation) · median 1 year

Highest incidence in KDIGO high-risk group; independent of other risk factors

Original publication

Chronic Kidney Disease Screening in Patients With Coronary Heart Disease. J Am Coll Cardiol. Published 1 April 2026. doi:10.1016/j.jacc.2026.01.075

Summarised from the published abstract; every number is checked against it