Congenital heart diseaseCohort study

Chronic Medication Burden After Cardiac Surgery for Pediatric Medicaid Beneficiaries

J Am Coll CardiolPublished

  • Retrospective cohort study

Authors' conclusion

Children who undergo cardiac surgery experience high medication burden that persists throughout childhood.

Study context

Population
New York State pediatric Medicaid enrollees age <18 years, 2006–2019
Exposure
Children who underwent cardiac surgery vs general pediatric population
  • Cardiac enrolleesn = 5,459
  • Noncardiac enrolleesn = 4.5 millionreference
Outcome
Total chronic medications per person-year, enrollees per 100 person-years using ≥1 and ≥3 medications, and medication expenditures per person-year

Main finding

As reported in the abstract

  • Cardiac enrollees using ≥1 chronic medication: more than 4 in 10, vs approximately 1 in 10 noncardiac enrollees
  • Medication expenditures per person-year 10 times higher for cardiac vs noncardiac enrollees

Observational data: associations, not effects.

Further findings

Chronic medication use among cardiac enrollees, by characteristics

Disease severity associated with chronic medication use; use highest among infants; nearly one-half of adolescents used ≥1 chronic medication

Original publication

Chronic Medication Burden After Cardiac Surgery for Pediatric Medicaid Beneficiaries. J Am Coll Cardiol. Published 26 September 2023. doi:10.1016/j.jacc.2023.06.046

Summarised from the published abstract; every number is checked against it