Prevention & lipidsGuideline or statement

Clinical staging to guide management of metabolic disorders and their sequelae: a European Atherosclerosis Society consensus statement

Eur Heart JPublished

  • Consensus statement

Recommendations

As issued by the authors

  1. Stage 1: metabolic abnormalities (e.g. dysfunctional adiposity, dyslipidaemia) without detectable organ damage

  2. Stage 2: early organ damage — T2DM, asymptomatic diastolic dysfunction, metabolic-associated steatohepatitis (MASH), chronic kidney disease (CKD)

  3. Stage 3: more advanced organ damage affecting multiple organs

  4. Management: lifestyle changes, pharmacotherapy, and metabolic surgery in severe cases

Original publication

Clinical staging to guide management of metabolic disorders and their sequelae: a European Atherosclerosis Society consensus statement. Eur Heart J. Published 7 May 2025. doi:10.1093/eurheartj/ehaf314

Summarised from the published abstract; every number is checked against it