Acute cardiac care & resuscitationCohort study
Clinical Use of Bedside Portable Ultra–Low-Field Brain Magnetic Resonance Imaging in Patients on Extracorporeal Membrane Oxygenation: Results From the Multicenter SAFE MRI Extracorporeal Membrane Oxygenation (ECMO) Study
- Prospective observational study
- multicenter
- 2 tertiary centers
Authors' conclusion
Our study demonstrates that ULF-pMRI can be performed in patients on ECMO across different ECMO cannulation strategies in specially trained intensive care units. The incidence of ABI was high, seen in 44% of ULF-pMRI studies. ULF-pMRI imaging appears to be more sensitive to ABI, particularly ischemic stroke, compared with head computed tomography.
Study context
- Population
- Patients on ECMO in specially trained ICUs53 eligible
- Participants
- 50 patients
- Exposure
- Venoarterial ECMO vs Venovenous ECMO
- Venoarterial ECMOn = 34
- Venovenous ECMOn = 16
- Outcome
- Safety of ULF-pMRI during ECMO support: completion without significant adverse events
Main finding
As reported in the abstract
Patients with adverse events
3 (6%)
Minor adverse events (ECMO suction event; transient low ECMO flow)
2
Serious adverse event (intra-aortic balloon pump malfunction from ECG artifacts)
1
Observational data: associations, not effects.
Further findings
Acute brain injury (ABI) frequency and type on ultra-low-field (ULF)-pMRI
- ABI
- 22 (44%)
- Ischemic stroke
- 36%
- Intracranial hemorrhage
- 6%
- Hypoxic-ischemic brain injury
- 4%
ULF-pMRI vs head CT within 24 hours
- Patients with both scans
- 18 (36%)
- Ischemic events seen on portable magnetic resonance imaging (pMRI)
- 8 of 8
- Ischemic events seen on head CT
- 4
- Hemorrhagic events seen on pMRI
- 1 of 2
- Hemorrhagic events seen on head CT
- 2
Safety
Adverse events
- Adverse events
- 3 (6%)
- Serious adverse event
- 1
Original publication
Summarised from the published abstract; every number is checked against it