Arrhythmias & electrophysiology
Clinical utility of systolic left ventricular ejection fraction in atrial fibrillation: Role of prospective ECG-triggered cardiac CT
Authors' conclusion
LVEF100ms can provide a useful indicator of LV dysfunction in patients with AF undergoing prospective electrocardiogram-triggered cardiac computed tomography.
Study context
- Population
- Patients with atrial fibrillation (AF) who underwent prospective systolic electrocardiogram-triggered cardiac computed tomographypatients analysed, categorized by echocardiographic LV ejection fraction (LVEF) · LVEF of ≥55% 62 (50.4%) · LVEF of 40%-50% 40 (32.5%) · LVEF of ≤40% 21 (17.1%)
- Participants
- 123 patients
- Index test or model
- LVEF100ms vs echocardiography-derived LVEF
- Target condition
- LVEF ≤ 40%
Methodological detailsscreened January 2015 to June 2023
- Screened January 2015 to June 2023
Performance
As reported in the abstract
Area under the curve
0.809
Sensitivity
87%
Specificity
67%
Further findings
Correlation of LVEF100ms with echocardiography-derived LVEF
- LVEF100ms correlated with echocardiography-derived LVEF
- P < 0.001
LVEF100ms across echocardiographic LVEF groups
- LVEF100ms differed significantly among groups
- P < 0.001
Major adverse cardiovascular events (MACE) (cardiac death, myocardial infarction, heart failure hospitalization, and stroke)
- Higher rate of MACE with LVEF100ms ≤3.3% than without
- P = 0.030
- LVEF100ms ≤ 3.3% was an independent predictor of MACE
- Cox proportional hazards models
Original publication
Clinical utility of systolic left ventricular ejection fraction in atrial fibrillation: Role of prospective ECG-triggered cardiac CT. Heart Rhythm. Published 23 January 2025. doi:10.
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